Metabolomix+ Comprehensive Nutritional, Organic Acids, plus 8-OHdG

Metabolomix+ Comprehensive Nutritional, Organic Acids & Oxidative Stress Assessment

The Genova Metabolomix+ is an advanced nutritional and metabolic assessment that combines a comprehensive organic acids profile with amino acids, nutrient and toxic elements, and direct measurements of oxidative cellular damage.

Unlike a standard organic acids test, Metabolomix+ evaluates several interconnected areas that may contribute to fatigue, mood or cognitive symptoms, poor stress tolerance, inflammation, impaired detoxification, digestive imbalance, and reduced mitochondrial energy production.

What This Test Evaluates

The Metabolomix+ assessment includes:

• Cellular energy and mitochondrial function
• Organic acids and Krebs cycle metabolites
• Functional B-vitamin needs, including B1, B2, B3, B6, biotin, folate, and B12
• Amino acids and amino-acid metabolism
• Methylation-related markers
• Neurotransmitter metabolites, including serotonin, catecholamine, and kynurenine-pathway markers
• Digestive, malabsorption, bacterial dysbiosis, and yeast-related markers
• Oxalate metabolism
• Glutathione and detoxification pathways
• Nutrient minerals and toxic elements
• Personalized antioxidant, mineral, amino-acid, digestive, and nutritional support needs

The report organizes findings into functional categories such as mitochondrial dysfunction, oxidative stress, methylation imbalance, toxic exposure, and nutritional support needs.

Includes 8-OHdG and Lipid Peroxides

This panel also includes the two oxidative-damage markers offered separately in the Advanced Mitochondrial & Oxidative Stress Panel:

8-Hydroxy-2′-deoxyguanosine (8-OHdG) measures oxidative damage to DNA. Elevated levels may indicate that free-radical activity is exceeding the body’s antioxidant and cellular-repair capacity.

Urinary lipid peroxides measure oxidative damage to cell-membrane fats. These markers can help identify excessive oxidative stress affecting mitochondrial membranes, neurological tissue, cardiovascular health, and general cellular function.

Including both markers makes Metabolomix+ especially useful for evaluating whether metabolic abnormalities are accompanied by measurable DNA and lipid damage. The sample report lists both 8-OHdG and urinary lipid peroxides within its oxidative-stress assessment.

Who May Benefit From This Assessment?

Metabolomix+ may be considered when evaluating:

• Persistent fatigue or poor exercise recovery
• Suspected mitochondrial dysfunction
• Brain fog, memory, mood, or concentration concerns
• Complex nutritional deficiencies
• Digestive dysfunction or suspected dysbiosis
• Oxidative stress or chronic inflammatory burden
• Poor response to supplements
• Suspected impaired detoxification
• Environmental or toxic-element exposure
• Unexplained metabolic symptoms involving several body systems

Why Choose Metabolomix+?

Many routine blood tests measure the amount of a nutrient circulating in the bloodstream. Metabolomix+ goes further by examining metabolic byproducts that may reveal how nutrients are being used inside biochemical pathways.

This provides a broader picture of:

• Where energy production may be impaired
• Which nutrients may be functionally insufficient
• Whether methylation or detoxification pathways require support
• Whether digestive imbalance may be influencing nutrient status
• Whether oxidative stress has caused measurable DNA or lipid damage
• Which interventions may deserve priority rather than relying on generalized supplementation

The result is a detailed, pathway-based assessment that can help guide a more individualized nutritional and mitochondrial support plan.