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      • Methylation Panel – Doctors Data
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      • Culture, PCR + Parasitology (CPP)
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    • Epigenetic Individual Tests
      • 8-0HdG
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      • GDF-15 Blood Test
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      • Magnesium RBC Test
      • Manganese Blood Test
    • Other Popular Lab Panels
      • Apolipoprotein B (Lipids)
      • Bredesens Cognoscopy – Alzheimer’s
      • Cholesterol w basic lipids
      • Cortisol – Salivary
      • Female Hormone Panel
      • Folate Receptor Antibody (FRAT Test)
      • Hashimoto’s Thyroid Panel
      • Testosterone, Free/Total
    • Common Lab Findings
      • Low Zinc Copper Ratio: Causes, Anxiety, ADHD and Dementia
      • Copper Overload
      • Low Ceruloplasmin & Free Copper
      • High Histamine
      • Elevated Homocysteine
      • High Urine Pyrroles
      • Elevated SAH & Low SAM
      • High Basophils
      • View All Lab Findings
  • The Walsh Approach
    • For Patients
      • The Walsh Approach
      • Five Biotypes of Depression
      • – Undermethylation
      • – Overmethylation
      • – Copper Overload
      • – Pyroluria
      • – Toxic Overload
      • What is WalshDoc?
    • For Practitioners
      • Walsh Protocol Training & Education
      • Bring the Walsh Approach into Your Practice
      • Understanding the Methylation Test
      • Homocysteine and Methylation
      • SAH, Methylation, and Mood
      • Walsh Protocol Nonresponders
      • Five Epigenetic Biotypes of Undermethylation
    • Research
      • Second Opinion Articles Hub
      • What Causes Postpartum Depression?
      • Genetic Testing vs Epigenetic & Functional Testing
      • What Causes Undermethylation?
      • Why Folic Acid Can Worsen Depression
      • Walsh Research and Publications
      • Walsh Research Institute – William Walsh, PhD
      • Benefits of Saunas for Detoxification
  • General Info
    • BLOG & ARTICLES
      • Blog Posts Overview
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      • What Causes Undermethylation?
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Key Tests and Consultation Items
  • Consultations
    • Doctor Consultations
    • Free Walsh Protocol Pre-Consultation
    • 15-Minute Telemedicine Phone Consultation
    • Walsh Protocol Biotype Assessment
    • Walsh Protocol Biotype + Methylation Assessment
    • Follow-Up Assessment — Biotype Labs Review with Report
    • Follow-Up Consultation – Updated Assessment | Biotype Labs + Methylation Panel
    • Comprehensive Functional Medicine Second Opinion Assessment
    • FRAT + Consultation
  • Conditions
    • ADHD
    • Anxiety
    • Autism
    • Bipolar Disorder
    • Dementia
    • Dysautonomia
    • Histamine
    • Insomnia
    • Kidney Toxicity
    • Liver Toxicity
    • Mitochondrial Dysfunction
    • Oxidative Stress
    • OCD – Obsessive Compulsive Disorder
    • Schizophrenia
  • Medications
    • Choosing the Best Antidepressant
    • SSRIs Explained
    • SNRIs Explained
    • ADHD Medications
    • Mood Stabilizers
    • Antipsychotics Medications
  • Labs
    • All Biotype Panels
      • Comprehensive Biotype Panel
      • Methylation Panel – Genova
      • Methylation Panel – Doctors Data
      • Copper Overload Biotype Panel
      • Hair Mineral and Toxic Elements
      • MTHFR plus C677T and A1298C
    • Biotype Single Tests
      • WB Histamine
      • Homocysteine
      • Plasma Zinc Test
      • Copper
      • Ceruloplasmin
      • Pyrroles, Urine
      • Vitamin D
      • CBC
      • Metabolic Panel
      • Hair and Toxic Elements
    • Epigenetic Panels
      • Acylcarnitines Profile
      • Core Mitochondria Panel
      • MycoTOX Profile: Mold
      • Gut-Metabolic Organic Acids
      • Toxic Metals & Antioxidant
      • Allergy & Immune
      • Intestinal Permeability + Celiac
      • Culture, PCR + Parasitology (CPP)
      • Organic Acids, 8-OHdG
      • Vitamins, Minerals, Antioxidant Status
      • Glucose, Lipids, Insulin
    • Epigenetic Individual Tests
      • 8-0HdG
      • Coenzyme Q10, Total
      • Creatine Kinase-MB
      • GDF-15 Blood Test
      • Glutathione Blood Test
      • Magnesium RBC Test
      • Manganese Blood Test
    • Other Popular Lab Panels
      • Apolipoprotein B (Lipids)
      • Bredesens Cognoscopy – Alzheimer’s
      • Cholesterol w basic lipids
      • Cortisol – Salivary
      • Female Hormone Panel
      • Folate Receptor Antibody (FRAT Test)
      • Hashimoto’s Thyroid Panel
      • Testosterone, Free/Total
    • Common Lab Findings
      • Low Zinc Copper Ratio: Causes, Anxiety, ADHD and Dementia
      • Copper Overload
      • Low Ceruloplasmin & Free Copper
      • High Histamine
      • Elevated Homocysteine
      • High Urine Pyrroles
      • Elevated SAH & Low SAM
      • High Basophils
      • View All Lab Findings
  • The Walsh Approach
    • For Patients
      • The Walsh Approach
      • Five Biotypes of Depression
      • – Undermethylation
      • – Overmethylation
      • – Copper Overload
      • – Pyroluria
      • – Toxic Overload
      • What is WalshDoc?
    • For Practitioners
      • Walsh Protocol Training & Education
      • Bring the Walsh Approach into Your Practice
      • Understanding the Methylation Test
      • Homocysteine and Methylation
      • SAH, Methylation, and Mood
      • Walsh Protocol Nonresponders
      • Five Epigenetic Biotypes of Undermethylation
    • Research
      • Second Opinion Articles Hub
      • What Causes Postpartum Depression?
      • Genetic Testing vs Epigenetic & Functional Testing
      • What Causes Undermethylation?
      • Why Folic Acid Can Worsen Depression
      • Walsh Research and Publications
      • Walsh Research Institute – William Walsh, PhD
      • Benefits of Saunas for Detoxification
  • General Info
    • BLOG & ARTICLES
      • Blog Posts Overview
      • Genetics vs Epigenetics
      • Epigenetic Biotypes of Undermethylation
      • What Causes Undermethylation?
      • High Copper Symptoms
      • When Folates Cause Depression
      • Toxic Overload & Depression
    • GENERAL / ACCOUNT
      • About Us
      • Contact Us
      • My Account (Login/Orders)
      • Payment Information
      • Schedule An Appointment
      • Reschedule My Appointment
    • FREQUENTLY ASKED QUESTIONS
      • FAQs
    • SUPPLEMENTS
      • Undermethylation
      • Copper Overload
      • Overmethylation
      • Pyroluria
      • Toxic Overload
      • Homocysteine
      • Ceruloplasmin
  • Take the Test
    • AI Supported Medical Assessment
    • Take the Test
    • WalshDoc Biotype + Methylation Questionnaire
Dr Dave’s Blog
  • 15
    Sep
    Vitamin D Therapy Interview Comments Off on Vitamin D Therapy Interview
  • 03
    Sep
    Foods High in Glutamate: Food List, Hidden Sources Comments Off on Foods High in Glutamate: Food List, Hidden Sources
  • 31
    Aug
    Ferritin Testing: Iron Toxicity and Oxidative Stress Comments Off on Ferritin Testing: Iron Toxicity and Oxidative Stress
  • 29
    Aug
    Kidney Function, Bicarbonate, SAH & Methylation No Comments on Kidney Function, Bicarbonate, SAH & Methylation
  • 27
    Aug
    Thomas Levy MD, Liposomal Vitamin C Protocol Comments Off on Thomas Levy MD, Liposomal Vitamin C Protocol
  • 25
    Aug
    Blog Hub Post – Overview of Articles No Comments on Blog Hub Post – Overview of Articles
  • 24
    Aug
    Genetics vs Epigenetics No Comments on Genetics vs Epigenetics
  • 24
    Aug
    What Causes Postpartum Depression? No Comments on What Causes Postpartum Depression?
  • 23
    Aug
    Benefits of Saunas for Detoxification Comments Off on Benefits of Saunas for Detoxification
  • 20
    Aug
    Homocysteine and Methylation No Comments on Homocysteine and Methylation
Blog Tags
Alzheimer's Disease Anxiety Autism Ceruloplasmin Copper Overload Creatine Demand Dementia Depression Developmental Regression Dysautonomia Elevated SAH Epigenetics Five Epigenetic Biotypes Folate Folinic Acid Glutathione Gut Dysbiosis Gut Health Heavy Metals Histamine Histamine Intolerance Homocysteine Infections Inflammation Ketogenic Therapy Liver Detoxification Long COVID Mast Cell Activation Methylation Mitochondrial Dysfunction MTHFR Nutrient Deficiencies OCD Overmethylation Oxidative Stress Ozone Therapy Respiratory Infections SAM/SAH Ratio Sodium Bicarbonate Toxic Overload Undermethylation Vitamin D Walsh Approach William Walsh Zinc Deficiency
Five Biotypes of Depression
  • FAQs
  • Undermethylation
  • Overmethylation
  • Copper Overload
  • Pyroluria
  • Toxic Overload
  • Five Epigenetic Biotypes of Undermethylation
  • Take the Test!
Copyright 2026 © Second Opinion Physician, P.C.
  • ×
  • Consultations
    • Doctor Consultations
    • Free Walsh Protocol Pre-Consultation
    • 15-Minute Telemedicine Phone Consultation
    • Walsh Protocol Biotype Assessment
    • Walsh Protocol Biotype + Methylation Assessment
    • Follow-Up Assessment — Biotype Labs Review with Report
    • Follow-Up Consultation – Updated Assessment | Biotype Labs + Methylation Panel
    • Comprehensive Functional Medicine Second Opinion Assessment
    • FRAT + Consultation
  • Conditions
    • ADHD
    • Anxiety
    • Autism
    • Bipolar Disorder
    • Dementia
    • Dysautonomia
    • Histamine
    • Insomnia
    • Kidney Toxicity
    • Liver Toxicity
    • Mitochondrial Dysfunction
    • Oxidative Stress
    • OCD – Obsessive Compulsive Disorder
    • Schizophrenia
  • Medications
    • Choosing the Best Antidepressant
    • SSRIs Explained
    • SNRIs Explained
    • ADHD Medications
    • Mood Stabilizers
    • Antipsychotics Medications
  • Labs
    • All Biotype Panels
      • Comprehensive Biotype Panel
      • Methylation Panel – Genova
      • Methylation Panel – Doctors Data
      • Copper Overload Biotype Panel
      • Hair Mineral and Toxic Elements
      • MTHFR plus C677T and A1298C
    • Biotype Single Tests
      • WB Histamine
      • Homocysteine
      • Plasma Zinc Test
      • Copper
      • Ceruloplasmin
      • Pyrroles, Urine
      • Vitamin D
      • CBC
      • Metabolic Panel
      • Hair and Toxic Elements
    • Epigenetic Panels
      • Acylcarnitines Profile
      • Core Mitochondria Panel
      • MycoTOX Profile: Mold
      • Gut-Metabolic Organic Acids
      • Toxic Metals & Antioxidant
      • Allergy & Immune
      • Intestinal Permeability + Celiac
      • Culture, PCR + Parasitology (CPP)
      • Organic Acids, 8-OHdG
      • Vitamins, Minerals, Antioxidant Status
      • Glucose, Lipids, Insulin
    • Epigenetic Individual Tests
      • 8-0HdG
      • Coenzyme Q10, Total
      • Creatine Kinase-MB
      • GDF-15 Blood Test
      • Glutathione Blood Test
      • Magnesium RBC Test
      • Manganese Blood Test
    • Other Popular Lab Panels
      • Apolipoprotein B (Lipids)
      • Bredesens Cognoscopy – Alzheimer’s
      • Cholesterol w basic lipids
      • Cortisol – Salivary
      • Female Hormone Panel
      • Folate Receptor Antibody (FRAT Test)
      • Hashimoto’s Thyroid Panel
      • Testosterone, Free/Total
    • Common Lab Findings
      • Low Zinc Copper Ratio: Causes, Anxiety, ADHD and Dementia
      • Copper Overload
      • Low Ceruloplasmin & Free Copper
      • High Histamine
      • Elevated Homocysteine
      • High Urine Pyrroles
      • Elevated SAH & Low SAM
      • High Basophils
      • View All Lab Findings
  • The Walsh Approach
    • For Patients
      • The Walsh Approach
      • Five Biotypes of Depression
      • – Undermethylation
      • – Overmethylation
      • – Copper Overload
      • – Pyroluria
      • – Toxic Overload
      • What is WalshDoc?
    • For Practitioners
      • Walsh Protocol Training & Education
      • Bring the Walsh Approach into Your Practice
      • Understanding the Methylation Test
      • Homocysteine and Methylation
      • SAH, Methylation, and Mood
      • Walsh Protocol Nonresponders
      • Five Epigenetic Biotypes of Undermethylation
    • Research
      • Second Opinion Articles Hub
      • What Causes Postpartum Depression?
      • Genetic Testing vs Epigenetic & Functional Testing
      • What Causes Undermethylation?
      • Why Folic Acid Can Worsen Depression
      • Walsh Research and Publications
      • Walsh Research Institute – William Walsh, PhD
      • Benefits of Saunas for Detoxification
  • General Info
    • BLOG & ARTICLES
      • Blog Posts Overview
      • Genetics vs Epigenetics
      • Epigenetic Biotypes of Undermethylation
      • What Causes Undermethylation?
      • High Copper Symptoms
      • When Folates Cause Depression
      • Toxic Overload & Depression
    • GENERAL / ACCOUNT
      • About Us
      • Contact Us
      • My Account (Login/Orders)
      • Payment Information
      • Schedule An Appointment
      • Reschedule My Appointment
    • FREQUENTLY ASKED QUESTIONS
      • FAQs
    • SUPPLEMENTS
      • Undermethylation
      • Copper Overload
      • Overmethylation
      • Pyroluria
      • Toxic Overload
      • Homocysteine
      • Ceruloplasmin
  • Take the Test
    • AI Supported Medical Assessment
    • Take the Test
    • WalshDoc Biotype + Methylation Questionnaire
  • Login / Register
  • ×
  • ```
    ```
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