MYCOPLASMA PNEUMONIAE ANTIBODIES (IgG + IgM)

What This Test Measures

This panel evaluates antibodies to Mycoplasma pneumoniae, an atypical bacterial infection that can affect the respiratory system and trigger immune-mediated symptoms.

• IgM → suggests recent or active infection
• IgG → indicates past exposure or chronic immune activation

Clinical Use

Mycoplasma is a recognized trigger in PANS (Pediatric Acute-onset Neuropsychiatric Syndrome) and may contribute to:

• Sudden behavioral or mood changes
• Anxiety, OCD-like symptoms
• Chronic inflammation or immune dysregulation

Why It Matters

In patients with neuropsychiatric symptoms and negative strep testing, Mycoplasma can represent a non-strep infectious trigger driving immune activation.

Identifying this allows for more targeted treatment strategies.