Diet and Nutrition – Foundations for Methylation and Mood

Category: Diet and Nutrition

Diet and nutrition form the foundation of biochemical balance, directly influencing inflammation, methylation, and brain chemistry. A Mediterranean-style diet—rich in colorful vegetables, healthy fats, fish, nuts, legumes, and modest portions of lean protein—supports stable blood sugar, provides essential minerals for enzyme activity, and lowers inflammatory load. Intermittent fasting can further improve insulin sensitivity, promote autophagy, and reduce oxidative stress, giving the body time to repair and reset detox and methylation pathways. Posts in this section highlight how diet influences neurotransmitters, copper–zinc balance, and liver function, and why processed foods, refined starches, and excess fructose can worsen symptoms of depression and fatigue. Nutrient-dense eating combined with time-restricted feeding helps optimize homocysteine metabolism, support SAM and glutathione production, and calm the inflammatory and oxidative cycles that underlie many mood and metabolic disorders. The goal is to use food and rhythm of eating as daily tools to support both mental and physical resilience.

The Cholesterol Myth – What’s good, what’s bad and what to test.

The Truth About Cholesterol: Why It’s Not the Villain You Think For decades, we’ve been [...]

Undermethylation and Autism

Undermethylation in Autism – What the Plasma Methylation Panel and SAM:SAH Ratio Reveal Methylation is [...]

Copper, Oxidative Stress, and Autism

Copper, Oxidative Stress, and Autism – The Hidden Chemistry Behind Behavior Copper and zinc are [...]

Autism & Mitochondrial Dysfunction

Methylation and Mitochondrial Dysfunction in Autism Autism is often discussed in terms of behavior or [...]

Histamine, Methylation and Serotonin. Treating depression with folic acid is usually not a good idea!

Why MTHFR genetic test and therapy with methylated folates is not advisable for treating undermethylated [...]

Low Glycemic Mediterranean (Methylation) Diet

Low-Glycemic Mediterranean Diet A low-glycemic Mediterranean diet supports methylation, mood, and metabolic stability by combining [...]

Lower Cholesterol Without Statins

Lower Cholesterol Without Statins This page explains how to lower risk with diet-first changes, targeted [...]

Creatine Improves Methylation; A Strategy for Creatine Supplemenation

Creatine Improves Methylation Creatine Supplementation: A Second Opinion Physician Hypothesis to Reduce Methylation Demand in [...]

Diet, Environment and Subtle Influences on Body pH; Alkalinity and Acidity

Chronic Low Grade Acidosis and the Need for Alkalinization to Improve Methylation Modern lifestyles often [...]

Improve Methylation with Sodium Bicarbonate: Raise pH to Lower SAH

Enzymes and Kidney Function: How Baking Soda Improves Methylation by Raising pH to lower SAH. [...]

0