Methylation Pathway | Second Opinion Physician

Category: Methylation Pathway

The methylation pathway controls how your body makes and breaks down neurotransmitters, detoxifies, and repairs DNA. Imbalances in the methylation pathway can lead to depression, anxiety, OCD, autism traits, and cognitive changes. Here we explore SAM/SAH balance, folate and B12, homocysteine, creatine demand, and pH-related issues that guide targeted nutrient therapy.

Folic acid worsens depression | Why MTHFR testing fails depression treatment

SECOND OPINION SERIES Folic Acid Worsens Depression | Why MTHFR Testing Fails This article explains [...]

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Walsh Protocol Explained: Nutrient Therapy for Depression, Folate Risks, and Key Nutrients

SECOND OPINION SERIES Walsh Protocol Explained: Why Nutrient Therapy Works When Psychiatric Labels Fail The [...]

Creatine and Methylation | How Creatine Supports SAMe & Mood

SECOND OPINION SERIES Creatine Improves Methylation | Supplementation Strategy This article explains how creatine improves [...]

Understanding Methylation: Symptoms, Histamine Balance, and the Best Tests for Mental Health

SECOND OPINION SERIES What Does Methylation Mean in the Body? Methylation is one of the [...]

Natural Treatment for OCD Symptoms | Understanding Glutamate, NMDAR & Biochemical Patterns

SECOND OPINION SERIES Natural Treatment for OCD Symptoms | Understanding Glutamate, NMDAR & Biochemical Patterns [...]

Understanding the Methylation Test: How to Identify Undermethylation and Nutrient Imbalances

Understanding the Methylation Test: How to Identify Undermethylation and Biochemical Imbalances Many people learn about [...]

Homocysteine and Methylation | Manage Homocysteine to Help Undermethylators

Homocysteine – Understanding Homocysteine and Methylation: A Functional Medicine Perspective Homocysteine sits at the center [...]

OCD Methylation and Mitochondria: Ketone Ester Therapy

OCD Methylation and Mitochondria: Ketone Ester Therapy & Metabolic Treatment OCD methylation and mitochondria are [...]

Undermethylation and Autism

Undermethylation in Autism – What the Plasma Methylation Panel and SAM:SAH Ratio Reveal Methylation is [...]

Undermethylation, Autism & Mitochondria

Undermethylation, Autism and Mitochondrial Dysfunction Autism is often discussed in terms of behavior or learning, [...]

Low Glycemic Mediterranean (Methylation) Diet

Low-Glycemic Mediterranean Diet A low-glycemic Mediterranean diet supports methylation, mood, and metabolic stability by combining [...]

Folinic Acid for Autism – FRAT Testing

Leucovorin for Autism: What Parents and Clinicians Should Know Families and clinicians are exploring whether [...]

Low Brain Folate in Autism

Cerebral Folate Deficiency in Autism Low Brain Folate in Autism, Seizures, and Neurological Disorders: Why [...]

How to Remove Toxins & Improve Methylation

How to Detoxify the Kidneys to Improve Methylation: Insights from Dr. Robin Rose The kidneys [...]

The Walsh Approach: Improve Methylation with Creatine & Baking Soda

Dr William Walsh & David Epstein, D.O. Discuss A Novel Approach to Improve Methylation: Alkalinity, [...]

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