Category: Metabolic Ketone Therapy

Metabolic dysfunction is one of the most overlooked drivers of neurological and psychiatric symptoms. Many patients with OCD, bipolar disorder, schizophrenia, dysautonomia, Parkinson’s disease, epilepsy, Alzheimer’s disease, autism, inflammatory bowel disorders, chronic fatigue, or PANS/PANDAS show clear signs of impaired mitochondrial function, glucose hypometabolism, oxidative stress, and NMDAR dysregulation. These metabolic patterns overlap with the biochemical imbalances identified in the Walsh Protocol—especially undermethylation, elevated histamine, copper overload, and impaired antioxidant capacity (low glutathione, high SAH). Ketogenic therapy supports these patients by shifting the brain from unstable glucose metabolism to clean ketone-based fuel, improving ATP production, lowering neuroinflammation, balancing glutamate and GABA, and stabilizing NMDAR activity. Research continues to show that ketone bodies reduce IL-6, TNF-α, and microglial activation while improving cognitive and emotional regulation. This category explores how ketone therapy, combined with targeted nutrient treatment, can help stabilize symptoms when conventional treatments fall short or when lab patterns strongly suggest metabolic stress and oxidative burden.