Category: Anxiety
Anxiety is one of the most common symptoms across several Walsh biotypes, particularly copper overload, pyroluria, and overmethylation. Each contributes to heightened stress sensitivity and neurotransmitter imbalance in distinct ways. In copper overload, excess copper increases dopamine conversion to norepinephrine, producing a state of overstimulation, tension, and panic. Pyroluria adds to this by depleting zinc and vitamin B6, nutrients needed for GABA and serotonin synthesis—leading to inner agitation, poor stress tolerance, and social withdrawal. Overmethylation, in contrast, involves elevated serotonin and dopamine activity, often with low whole blood histamine, producing anxiety, sleep disturbance, and emotional volatility that worsen with SSRI or SNRI medications. Posts in this section explain how to identify each pattern through lab markers such as copper, zinc, ceruloplasmin, pyrroles, and histamine, and how to correct the biochemical cause rather than suppress symptoms. Targeted nutrient therapy, stress management, and detox support together help calm the nervous system and restore a more balanced, resilient emotional state.
Pyroluria: Why It Causes Anxiety, Sleep Trouble & Learning Issues
Pyroluria (Pyrrole Disorder): Understanding the Root Cause Some children and adults struggle with anxiety, mood [...]
Zinc Deficiency | Meaning, Symptoms and Testing
Zinc Deficiency Meaning Zinc deficiency refers to the condition where there is insufficient zinc in [...]
The Link Between Obesity, Estrogen, Copper, and Anxiety
Obesity, Estrogen, and Copper: A Complex Relationship with Health Implications Obesity is a medical condition [...]
Raising Ceruloplasmin to Improve Copper Overload Symptoms
Copper Imbalance: Causes, Symptoms and Increasing Ceruloplasmin to Improve Free Copper What is Ceruloplasmin? Ceruloplasmin [...]
Copper Overload and Depression
Copper Overload and its Physical and Neurological Symptoms Copper overload, also known as copper toxicity [...]
Copper Toxicity – A Common Cause of Psychiatric Symptoms and How to Treat It with Zinc and Nutrients
Copper Toxicity; Science, Symptoms, Therapy The Five Biotypes of Depression: Copper Overload William Walsh, PhD, [...]
Benzodiazepine Withdrawal
Dr. Ashton, DR, FRCP, is an Emeritus Professor of Clinical Psycho-pharmacology at the University of [...]
The Role of Pyrroles in Depression
##kryptopyrrole, also known as pyroluria or mauve factor, is a condition in which elevated levels [...]
