Category: Walsh Protocol & Biotypes
The Walsh Protocol identifies five core biochemical patterns—called the Five Biotypes of Depression—that explain why people respond differently to medications, supplements, and stress. These biotypes include undermethylation, overmethylation, copper overload, pyroluria, and toxic overload. Each pattern reflects a distinct imbalance in neurotransmitter activity, nutrient status, and gene regulation that can be measured through targeted lab testing. Posts in this section explain how to recognize each biotype through symptoms and lab markers such as histamine, SAM/SAH, copper, zinc, ceruloplasmin, pyrroles, and homocysteine, and how personalized nutrient therapy can restore balance. The goal is to replace trial-and-error psychiatry with a biochemical roadmap—helping identify which nutrients to use, which to avoid, and how to address the root causes of mood and behavior changes using evidence-based nutritional psychiatry.
Alzheimer’s and MT Promoter Therapy
Notes from a physician workshop given by Dr William Walsh, Phd., 2016 Treatment of Alzheimer’s [...]
Toxic Overload, Depression and Detoxification Pathways
Toxic Overload and Depression: The Effect of Toxins on Methylation and Glutathione Depletion This article [...]
The Link Between Obesity, Estrogen, Copper, and Anxiety
Obesity, Estrogen, and Copper: A Complex Relationship with Health Implications Obesity is a medical condition [...]
Histamine Intolerance and Mental Health | Depression, Anxiety & Natural Treatment
SECOND OPINION SERIES Histamine Intolerance and Mental Health Causes, Depression, and Natural Treatment Through Gut [...]
The Crucial Role of Methylation, Folate and Niacin in Depression Treatment – Summarized
High Intensity Health Interviews Dr William Walsh PhD 2018 Methylation, Folate, and Niacin in Mental [...]
William Walsh PhD. Video – Methylation, Pregnancy and Mood Disorders – Summarized
Epigenetics, Methylation Mental Health & Preconception Planning w/ Bill Walsh, PhD Methylation is a critical [...]
Treat Elevated Histamine, Naturally
Managing Histamine Intolerance with Methylation & Nutrient Therapy Histamine intolerance is a condition in which [...]
Copper Overload and Post Partum Depression
Copper Toxicity and Postpartum Depression (PPD) Postpartum depression (PPD) is a common mental health disorder [...]
Depression and the Methylation Pathway
Methylation and Depression What is Methylation? Methylation is not one specific reaction that occurs in [...]
Ozone Therapy for Detoxification and Enhanced Health
Ozone Therapy: A Controversial Yet Promising Treatment Despite its potential benefits, ozone therapy remains a [...]
Barriers to Success with the Walsh Approach
Before spending money on Walsh Panel testing, or a medical Consultation it is advisable to [...]
Benzodiazepine Withdrawal
Dr. Ashton, DR, FRCP, is an Emeritus Professor of Clinical Psycho-pharmacology at the University of [...]
Dave Asprey Interviews Dr William Walsh PhD. | Nutrition and Neurotransmitter Function
Dr Walsh Interview with Dave Asprey. Discussing Nutrition and Neurotransmitter Function. Summary with time stamps: [...]
Bulletproof Interview with Bill Walsh PhD – Transcript
Follow Along with the Radio Interview Announcer: Bulletproof Radio, a state of high performance. Dave: [...]
Mast Cell Activation Disorder – MCAD – Signs and Symptoms
Because of the widespread anomalies that exist in so many tissues, relating to mast cell, [...]