Description
Fasting Required: No
Specimen: Blood
Results: 4-10 Business Days
Description:
Thyroglobulin is a protein that is found primarily in the thyroid gland. Some thyroglobulin can be found in the blood. This blood test also looks for antibodies made by your body in response to thyroglobulin. Thyroglobulin antibodies attack thyroglobulin proteins and can destroy the thyroid gland itself. The test can be used to distinguish an autoimmune thyroid disease from other thyroid diseases. For example, to find the causes of goiters or high/low thyroid hormone levels.
Includes: Thyroglobulin, Thyroglobulin Antibodies
Methodology: Immunoassay (IA)
Clinical Significance: Thyroglobulin (TG) is a secretory product only of the thyroid gland. The major clinical use of serum TG measurement is to monitor, but not to diagnose, patients with well-differentiated thyroid cancers. The measurement of thyroglobulin, after thyroidectomy and ablation of the thyroid gland, is useful to determine metastasis. Deficient TG synthesis is observed in infants with goitrous hypo-thyroidism. Most patients with thyroid autoimmune disease have thyroglobulin antibody. With immunometric assays (sandwich assays), TGAB interference typically produces inappropriately low TG results, most likely caused by endogenous TG immune complexes that block one or more of the reagent antibodies from binding endogenous TG.
Alternative Name(s): TG and ATG,ATG and TG
Note: Result turn around times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.