Diet and Nutrition – Foundations for Methylation and Mood

Category: Therapeutic Diets & Ketones

Diet and nutrition form the foundation of biochemical balance, directly influencing inflammation, methylation, and brain chemistry. A Mediterranean-style diet—rich in colorful vegetables, healthy fats, fish, nuts, legumes, and modest portions of lean protein—supports stable blood sugar, provides essential minerals for enzyme activity, and lowers inflammatory load. Intermittent fasting can further improve insulin sensitivity, promote autophagy, and reduce oxidative stress, giving the body time to repair and reset detox and methylation pathways. Posts in this section highlight how diet influences neurotransmitters, copper–zinc balance, and liver function, and why processed foods, refined starches, and excess fructose can worsen symptoms of depression and fatigue. Nutrient-dense eating combined with time-restricted feeding helps optimize homocysteine metabolism, support SAM and glutathione production, and calm the inflammatory and oxidative cycles that underlie many mood and metabolic disorders. The goal is to use food and rhythm of eating as daily tools to support both mental and physical resilience.

Rhonda Patrick, PhD. Interviews Dale Bredesen MD Alzheimers

This video interviews Dale E. Bredesen, M.D., a neurology professor at the Easton Laboratories for [...]

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